Issue 22, 2015

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Abstract

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Graphical abstract: Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Supplementary files

Article information

Article type
Communication
Submitted
26 Aug 2015
Accepted
28 Sep 2015
First published
28 Sep 2015

Lab Chip, 2015,15, 4277-4282

Author version available

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Z. Ao, E. Parasido, S. Rawal, A. Williams, R. Schlegel, S. Liu, C. Albanese, R. J. Cote, A. Agarwal and R. H. Datar, Lab Chip, 2015, 15, 4277 DOI: 10.1039/C5LC01024A

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