Jump to main content
Jump to site search

Issue 36, 2015
Previous Article Next Article

Ultrafast non-radiative decay of gas-phase nucleosides

Author affiliations

Abstract

The ultrafast photo-physical properties of DNA are crucial in providing a stable basis for life. Although the DNA bases efficiently absorb ultraviolet (UV) radiation, this energy can be dissipated to the surrounding environment by the rapid conversion of electronic energy to vibrational energy within about a picosecond. The intrinsic nature of this internal conversion process has previously been demonstrated through gas phase experiments on the bases, supported by theoretical calculations. De-excitation rates appear to be accelerated when individual bases are hydrogen bonded to solvent molecules or their complementary Watson–Crick pair. In this paper, the first gas-phase measurements of electronic relaxation in DNA nucleosides following UV excitation are reported. Using a pump–probe ionization scheme, the lifetimes for internal conversion to the ground state following excitation at 267 nm are found to be reduced by around a factor of two for adenosine, cytidine and thymidine compared with the isolated bases. These results are discussed in terms of a recent proposition that a charge transfer state provides an additional internal conversion pathway mediated by proton transfer through a sugar to base hydrogen bond.

Graphical abstract: Ultrafast non-radiative decay of gas-phase nucleosides

Back to tab navigation

Publication details

The article was received on 01 Jul 2015, accepted on 13 Aug 2015 and first published on 13 Aug 2015


Article type: Paper
DOI: 10.1039/C5CP03806E
Citation: Phys. Chem. Chem. Phys., 2015,17, 23643-23650
  • Open access: Creative Commons BY license
  •   Request permissions

    Ultrafast non-radiative decay of gas-phase nucleosides

    S. D. Camillis, J. Miles, G. Alexander, O. Ghafur, I. D. Williams, D. Townsend and J. B. Greenwood, Phys. Chem. Chem. Phys., 2015, 17, 23643
    DOI: 10.1039/C5CP03806E

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements