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Issue 6, 2016
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Switching first contact: photocontrol of E. coli adhesion to human cells

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Abstract

We have shown previously that carbohydrate-specific bacterial adhesion to a non-physiological surface can be photocontrolled by reversible E/Z isomerisation using azobenzene-functionalised sugars. Here, this approach is applied to the surface of human cells. We show not only that bacterial adhesion to the azobenzene glycoside-modified cell surface is higher in the E than in the Z state, but add data about the specific modulation of the effect.

Graphical abstract: Switching first contact: photocontrol of E. coli adhesion to human cells

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Publication details

The article was received on 28 Oct 2015, accepted on 18 Nov 2015 and first published on 19 Nov 2015


Article type: Communication
DOI: 10.1039/C5CC08884D
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Citation: Chem. Commun., 2016,52, 1254-1257
  • Open access: Creative Commons BY-NC license
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    Switching first contact: photocontrol of E. coli adhesion to human cells

    L. Möckl, A. Müller, C. Bräuchle and T. K. Lindhorst, Chem. Commun., 2016, 52, 1254
    DOI: 10.1039/C5CC08884D

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