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Issue 87, 2015
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MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

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Abstract

We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal–organic frameworks (MOFs). We show that the MOF@lipid system can effectively store dye molecules inside the porous scaffold of the MOF while the lipid bilayer prevents their premature release. Efficient uptake of the MOF@lipid nanoparticles by cancer cells makes these nanocarriers promising for drug delivery and diagnostic purposes.

Graphical abstract: MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

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Publication details

The article was received on 12 Aug 2015, accepted on 04 Sep 2015 and first published on 11 Sep 2015


Article type: Communication
DOI: 10.1039/C5CC06767G
Citation: Chem. Commun., 2015,51, 15752-15755
  • Open access: Creative Commons BY-NC license
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    MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

    S. Wuttke, S. Braig, T. Preiß, A. Zimpel, J. Sicklinger, C. Bellomo, J. O. Rädler, A. M. Vollmar and T. Bein, Chem. Commun., 2015, 51, 15752
    DOI: 10.1039/C5CC06767G

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