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Issue 98, 2015
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Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

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Abstract

In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.

Graphical abstract: Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

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Publication details

The article was received on 24 Jul 2015, accepted on 05 Oct 2015 and first published on 07 Oct 2015


Article type: Communication
DOI: 10.1039/C5CC06211J
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 17428-17430
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    Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

    S. Sugimoto, R. Moriyama, T. Mori and Y. Iwasaki, Chem. Commun., 2015, 51, 17428
    DOI: 10.1039/C5CC06211J

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