Issue 86, 2015

Electrochemical detection of type 2 diabetes mellitus-related SNP via DNA-mediated growth of silver nanoparticles on single walled carbon nanotubes

Abstract

Herein, we proposed a new electrochemical sensing strategy for T2DM-related SNP detection via DNA-mediated growth of AgNPs on a SWCNT-modified electrode. Coupled with RNase HII enzyme assisted amplification, this approach could realize T2DM-related SNP assay and be applied in crude extracts of carcinoma pancreatic β-cell lines.

Graphical abstract: Electrochemical detection of type 2 diabetes mellitus-related SNP via DNA-mediated growth of silver nanoparticles on single walled carbon nanotubes

Supplementary files

Article information

Article type
Communication
Submitted
04 Jul 2015
Accepted
12 Aug 2015
First published
27 Aug 2015

Chem. Commun., 2015,51, 15704-15707

Author version available

Electrochemical detection of type 2 diabetes mellitus-related SNP via DNA-mediated growth of silver nanoparticles on single walled carbon nanotubes

J. Tao, P. Zhao, J. Zheng, C. Wu, M. Shi, J. Li, Y. Li and R. Yang, Chem. Commun., 2015, 51, 15704 DOI: 10.1039/C5CC05520B

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