Issue 74, 2015
From the journal:

Chemical Communications

Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu–Pt complex†

Hongguang Li,a   Rongfeng Lan,a   Chi-Fai Chan,a   Lijun Jiang,a   Lixiong Dai,a   Daniel W. J. Kwong,*a   Michael Hon-Wah Lamb  and  Ka-Leung Wong*a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR
E-mail: dkwong@hkbu.edu.hk, klwong@hkbu.edu.hk

b Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR
E-mail: bhmhwlam@cityu.edu.hk

Abstract

A water-soluble light-responsive antitumor agent, PtEuL, based on a cisplatin-linked europium–cyclen complex has been synthesized and evaluated for controlled cisplatin release by linear/two-photon excitation in vitro with concomitant turn-on and long-lived europium emission as a responsive traceable signal.

Graphical abstract: Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu–Pt complex

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Article information

DOI
https://doi.org/10.1039/C5CC05461C
Article type
Communication
Submitted
02 Jul 2015
Accepted
30 Jul 2015
First published
30 Jul 2015

Chem. Commun., 2015,51, 14022-14025

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Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu–Pt complex

H. Li, R. Lan, C. Chan, L. Jiang, L. Dai, D. W. J. Kwong, M. H. Lam and K. Wong, Chem. Commun., 2015, 51, 14022 DOI: 10.1039/C5CC05461C

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