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Issue 77, 2015
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A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification

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Abstract

A plasmonic nanosensor (using gold nanorods) with inverse sensitivity is presented for circulating cell-free DNA quantification. The inverse sensitivity (i.e. the lower the analyte concentration, the higher the response intensity) is achieved by the unusual DNA concentration-dependent gold nanorod aggregation. This assay method can adjust the dynamic range by controlling the concentration of nanoparticles in solution.

Graphical abstract: A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification

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Publication details

The article was received on 29 Jun 2015, accepted on 06 Aug 2015 and first published on 06 Aug 2015


Article type: Communication
DOI: 10.1039/C5CC05331E
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 14524-14527
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    A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification

    R. M. Pallares, S. L. Kong, T. Hui Ru, N. T. K. Thanh, Y. Lu and X. Su, Chem. Commun., 2015, 51, 14524
    DOI: 10.1039/C5CC05331E

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