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Issue 73, 2015
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Amorphous metal–organic frameworks for drug delivery

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Abstract

We report the encapsulation of the hydrophilic model molecule calcein in the Zr-based MOF UiO-66, followed by amorphization of the framework by ball-milling. We show controlled release of calcein over more than 30 days, compared with the 2 day release period from crystalline UiO-66.

Graphical abstract: Amorphous metal–organic frameworks for drug delivery

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Publication details

The article was received on 25 Jun 2015, accepted on 21 Jul 2015 and first published on 21 Jul 2015


Article type: Communication
DOI: 10.1039/C5CC05237H
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 13878-13881
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    Amorphous metal–organic frameworks for drug delivery

    C. Orellana-Tavra, E. F. Baxter, T. Tian, T. D. Bennett, N. K. H. Slater, A. K. Cheetham and D. Fairen-Jimenez, Chem. Commun., 2015, 51, 13878
    DOI: 10.1039/C5CC05237H

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