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We report a novel ruthenium(II) complex for selective release of the imidazole-based drug econazole. While the complex is highly stable and luminescent in the dark, irradiation with green light induces release of one of the econazole ligands, which is accompanied by a turn-off luminescence response and up to a 34-fold increase in cytotoxicity towards tumour cells.
N. Karaoun and A. K. Renfrew, Chem. Commun., 2015, 51, 14038 DOI: 10.1039/C5CC05172J
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