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Issue 57, 2015
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The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

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Abstract

By using an acoustic wave methodology that allows direct sensing of biomolecular conformations, we achieved the detection of multiple target DNAs using a single probe, exploiting the fact that each bound target results in a hybridized product of a different shape.

Graphical abstract: The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

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Publication details

The article was received on 24 Apr 2015, accepted on 05 Jun 2015 and first published on 05 Jun 2015


Article type: Communication
DOI: 10.1039/C5CC03436A
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 11504-11507
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    The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

    A. Tsortos, A. Grammoustianou, R. Lymbouridou, G. Papadakis and E. Gizeli, Chem. Commun., 2015, 51, 11504
    DOI: 10.1039/C5CC03436A

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