Issue 74, 2015

Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues

Abstract

We report a novel ‘fluorescent dopamine’ that possesses essential features of natural dopamine. Our method is simple and is readily extended to monoamine neurotransmitters such as L-norepinephrine, serotonin and GABA, providing a more practical approach. Because of its compatibility with sensitive fluorescent measurements, we envisage that our approach will have a broad range of applications in neural research.

Graphical abstract: Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues

Supplementary files

Article information

Article type
Communication
Submitted
13 Apr 2015
Accepted
03 Aug 2015
First published
03 Aug 2015

Chem. Commun., 2015,51, 14080-14083

Author version available

Toward live-cell imaging of dopamine neurotransmission with fluorescent neurotransmitter analogues

H. Lin, H. Lu, K. Liu, C. Chau, Y. Hsieh, Y. Li and I. Liau, Chem. Commun., 2015, 51, 14080 DOI: 10.1039/C5CC03050A

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