Issue 47, 2015
From the journal:

Chemical Communications

Lipase-modified pH-responsive microgel-based optical device for triglyceride sensing†

Qiang Matthew Zhang,a   Darren Berg,b   Samuel M. Mugo*b  and  Michael J. Serpe*a  

* Corresponding authors

a Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2 Canada
E-mail: michael.serpe@ualberta.ca
Fax: +1 780 492 8231
Tel: +1 780 492 5778

b Physical Sciences Department, MacEwan University, 10700-104 Avenue, Edmonton, AB, T5J 4S2 Canada
E-mail: mugos@macewan.ca
Tel: +1 780 887 7026

Abstract

Lipase-modified pH-responsive poly(N-isopropylacrylamide)-based microgels were synthesized. An optical device was subsequently fabricated by sandwiching the enzyme loaded responsive microgels between two thin Au layers, and their response to triolein, a model triglyceride, was investigated. The device's response depended on the triglyceride concentration, demonstrating its potential application as a triglyceride biosensor.

Graphical abstract: Lipase-modified pH-responsive microgel-based optical device for triglyceride sensing

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Article information

DOI
https://doi.org/10.1039/C5CC02853A
Article type
Communication
Submitted
07 Apr 2015
Accepted
12 May 2015
First published
18 May 2015
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2015,51, 9726-9728

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Lipase-modified pH-responsive microgel-based optical device for triglyceride sensing

Q. M. Zhang, D. Berg, S. M. Mugo and M. J. Serpe, Chem. Commun., 2015, 51, 9726 DOI: 10.1039/C5CC02853A

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