An N-heterocyclic carbene-catalyzed enantioselective [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines was developed. The corresponding pyrazolidinones were obtained in good yields with moderate to good diastereoselectivities and excellent enantioselectivities.
![Graphical abstract: N-Heterocyclic carbene-catalyzed [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5CC01238D&imageInfo.ImageIdentifier.Year=2015)
Z. Gao, X. Chen, J. Cheng, W. Liao and S. Ye, Chem. Commun., 2015, 51, 9328 DOI: 10.1039/C5CC01238D
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