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Issue 19, 2015
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Photocontrolled chignolin-derived β-hairpin peptidomimetics

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Abstract

The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.

Graphical abstract: Photocontrolled chignolin-derived β-hairpin peptidomimetics

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Publication details

The article was received on 24 Dec 2014, accepted on 19 Jan 2015 and first published on 19 Jan 2015


Article type: Communication
DOI: 10.1039/C4CC10304A
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Citation: Chem. Commun., 2015,51, 4001-4004
  • Open access: Creative Commons BY-NC license
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    Photocontrolled chignolin-derived β-hairpin peptidomimetics

    T. Podewin, M. S. Rampp, I. Turkanovic, K. L. Karaghiosoff, W. Zinth and A. Hoffmann-Röder, Chem. Commun., 2015, 51, 4001
    DOI: 10.1039/C4CC10304A

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