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Issue 16, 2015
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Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes

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Abstract

The phototoxicity of Chlorin e6 (Ce6) for photodynamic therapy (PDT) was found to be effectively suppressed by indocyanine green (ICG), a near infrared (NIR) dye. Upon NIR laser irradiation at 808 nm, ICG in the liposomes containing ICG and Ce6 could be degraded, while the phototoxicity of Ce6 could be recovered. In addition, we demonstrate that this newly developed liposomal component can be successfully used for activatable PDT to destroy cancer cells in vitro.

Graphical abstract: Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes

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Publication details

The article was received on 04 Dec 2014, accepted on 08 Jan 2015 and first published on 08 Jan 2015


Article type: Communication
DOI: 10.1039/C4CC09689D
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 3340-3342
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    Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes

    A. Yuan, X. Tang, X. Qiu, K. Jiang, J. Wu and Y. Hu, Chem. Commun., 2015, 51, 3340
    DOI: 10.1039/C4CC09689D

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