Issue 2, 2016

Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin

Abstract

We report a new crosslinked polymersome with pH-responsive swelling properties through acidic hydrolysis of hydrophobic contents from the amphiphilic polymer chains. Its unique stability under physiological conditions and large swelling capability under low pH conditions give this polymersome promising potential for anticancer drug delivery.

Graphical abstract: Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin

Supplementary files

Article information

Article type
Communication
Submitted
22 Jul 2015
Accepted
14 Sep 2015
First published
07 Oct 2015

Biomater. Sci., 2016,4, 245-249

Author version available

Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin

X. Liu, M. J. Yaszemski and L. Lu, Biomater. Sci., 2016, 4, 245 DOI: 10.1039/C5BM00269A

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