Issue 29, 2014

Fluorene-based chemodosimeter for “turn-on” sensing of cyanide by hampering ESIPT and live cell imaging

Abstract

A new salicylaldehyde appended fluorene-based chemodosimeter (FSal) has been designed by taking consideration of the special nucleophilicity of cyanide ion. FSal shows selective affinity towards CN over other anions (namely F, Br, NO3, ClO4, N3, H2PO4, AcO, I, Cl, and NO2) through turn-on fluorescence with a minimum detection limit of 0.06 ppm. The turn-on fluorescence of the FSal–CN complex resulting from hampering ESIPT is also supported by DFT and TDDFT calculations. Biological compatibility and live cell imaging of this unique probe have also been explored.

Graphical abstract: Fluorene-based chemodosimeter for “turn-on” sensing of cyanide by hampering ESIPT and live cell imaging

Supplementary files

Article information

Article type
Paper
Submitted
10 Mar 2014
Accepted
23 Apr 2014
First published
24 Apr 2014

J. Mater. Chem. B, 2014,2, 4733-4739

Fluorene-based chemodosimeter for “turn-on” sensing of cyanide by hampering ESIPT and live cell imaging

M. K. Bera, C. Chakraborty, P. K. Singh, C. Sahu, K. Sen, S. Maji, A. K. Das and S. Malik, J. Mater. Chem. B, 2014, 2, 4733 DOI: 10.1039/C4TB00388H

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