Issue 21, 2014
From the journal:

Journal of Materials Chemistry B

Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy†

Jeong Hoon Byeon*a  and  Young-Woo Kim*b  

* Corresponding authors

a Department of Chemistry, Purdue University, Indiana 47907, USA
E-mail: jbyeon@purdue.edu
Tel: +1 765 494 5499

b Department of Automotive Engineering, Hoseo University, Asan 336-795, Republic of Korea
E-mail: ywkim@hoseo.edu
Tel: +82 41 540 5819

Abstract

The gene transfection efficiency of Au@PDMS–PLL soft nanocomposites was higher than those of SiO2–PLL and PEI; and moreover, the nanocomposites did not show significant cell cytotoxicity in in vitro measurements. The soft nanocomposites were also sensitive during photothermal therapy with infrared light, which produced a cytotoxic effect on the targeted HeLa cells.

Graphical abstract: Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

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Article information

DOI
https://doi.org/10.1039/C4TB00271G
Article type
Communication
Submitted
19 Feb 2014
Accepted
16 Mar 2014
First published
18 Mar 2014

J. Mater. Chem. B, 2014,2, 3185-3189

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Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

J. H. Byeon and Y. Kim, J. Mater. Chem. B, 2014, 2, 3185 DOI: 10.1039/C4TB00271G

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