Jump to main content
Jump to site search

Issue 3, 2014
Previous Article Next Article

Mechanism-guided design of flow systems for multicomponent reactions: conversion of CO2 and olefins to cyclic carbonates

Author affiliations

Abstract

A mechanism-guided design of a multi-step flow system enabled an efficient general process for the synthesis of cyclic carbonates from alkenes and CO2. The flow system proved to be an ideal platform for multicomponent reactions because it was straightforward to introduce reagents at specific stages without their interacting with each other or with reaction intermediates prone to destruction by them. This system exhibited superior reactivity, increased yield, and broader substrate scope relative to conventional batch conditions and suppressed the formation of undesired byproducts, such as, epoxides and 1,2-dibromoalkanes.

Graphical abstract: Mechanism-guided design of flow systems for multicomponent reactions: conversion of CO2 and olefins to cyclic carbonates

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 13 Dec 2013, accepted on 16 Jan 2014 and first published on 27 Jan 2014


Article type: Edge Article
DOI: 10.1039/C3SC53422G
Citation: Chem. Sci., 2014,5, 1227-1231
  •   Request permissions

    Mechanism-guided design of flow systems for multicomponent reactions: conversion of CO2 and olefins to cyclic carbonates

    J. Wu, J. A. Kozak, F. Simeon, T. A. Hatton and T. F. Jamison, Chem. Sci., 2014, 5, 1227
    DOI: 10.1039/C3SC53422G

Search articles by author