Issue 17, 2014
From the journal:

RSC Advances

Synthesis of (E)-3-styryl-2,5-dihydro-1H-pyrrole derivatives via Pd-catalyzed addition of indoles to hydroxy 1,6-enynes†

Mei-Jin Zhong,a   Hai-Tao Zhu,a   Pin Gao,a   Yi-Feng Qiua  and  Yong-Min Liang*a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
E-mail: liangym@lzu.edu.cn
Fax: +86-931-8912582

Abstract

A mild Pd-catalyzed addition of indoles to hydroxy 1,6-enynes has been developed. In this reaction, hydroxy 1,6-enynes were selectively transformed into (E)-3-styryl-2,5-dihydro-1H-pyrrole derivatives.

Graphical abstract: Synthesis of (E)-3-styryl-2,5-dihydro-1H-pyrrole derivatives via Pd-catalyzed addition of indoles to hydroxy 1,6-enynes

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Article information

DOI
https://doi.org/10.1039/C3RA47647B
Article type
Communication
Submitted
15 Dec 2013
Accepted
21 Jan 2014
First published
21 Jan 2014

RSC Adv., 2014,4, 8914-8917

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Synthesis of (E)-3-styryl-2,5-dihydro-1H-pyrrole derivatives via Pd-catalyzed addition of indoles to hydroxy 1,6-enynes

M. Zhong, H. Zhu, P. Gao, Y. Qiu and Y. Liang, RSC Adv., 2014, 4, 8914 DOI: 10.1039/C3RA47647B

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