Issue 9, 2014

Sonogashira cross-coupling under non-basic conditions. Flow chemistry as a new paradigm in reaction control

Abstract

The flow regime was implemented as a non-chemical alternative for the reaction control and detrimental acid byproduct sequestration in transition metal catalyzed cross-coupling reactions. The concept was illustrated on the Sonogashira reaction and resulted in a non-basic version of the cross-coupling protocols.

Graphical abstract: Sonogashira cross-coupling under non-basic conditions. Flow chemistry as a new paradigm in reaction control

Supplementary files

Article information

Article type
Research Article
Submitted
18 Jul 2014
Accepted
14 Aug 2014
First published
26 Aug 2014

Org. Chem. Front., 2014,1, 1067-1071

Author version available

Sonogashira cross-coupling under non-basic conditions. Flow chemistry as a new paradigm in reaction control

S. Voltrova and J. Srogl, Org. Chem. Front., 2014, 1, 1067 DOI: 10.1039/C4QO00198B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements