Issue 7, 2014

A convenient, economical and scalable multi-gram synthesis of 1-vinylcyclopropyl 4-methylbenzenesulfonate

Abstract

We describe a practical, economical, and scalable multi-gram synthesis of 1-vinylcyclopropyl 4-methylbenzenesulfonate. This intermediate is important for the rapid and economical synthesis of alkylidenecyclopropanes, which provides access to a variety of alicyclic systems via metal-catalysed higher-order carbocyclization and cycloisomerization reactions.

Graphical abstract: A convenient, economical and scalable multi-gram synthesis of 1-vinylcyclopropyl 4-methylbenzenesulfonate

Supplementary files

Article information

Article type
Tutorial Account
Submitted
24 Mar 2014
Accepted
20 May 2014
First published
01 Jul 2014

Org. Chem. Front., 2014,1, 821-824

Author version available

A convenient, economical and scalable multi-gram synthesis of 1-vinylcyclopropyl 4-methylbenzenesulfonate

O. S. Ojo, P. A. Inglesby, D. E. Negru and P. A. Evans, Org. Chem. Front., 2014, 1, 821 DOI: 10.1039/C4QO00089G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements