Issue 45, 2014
From the journal:

Organic & Biomolecular Chemistry

Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis†

Alexander S. Henderson,a   John F. Bower*a  and  M. Carmen Galan*a  

* Corresponding authors

a School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK
E-mail: john.bower@bris.ac.uk, m.c.galan@bris.ac.uk

Abstract

Versatile syntheses of C2-linked and C2-symmetric carbohydrate-based imidazol(in)ium salts from functionalised amino-carbohydrate derivatives are reported. The novel NHCs were ligated to [Rh(COD)Cl]2 and evaluated in Rh-catalysed asymmetric hydrosilylation of ketones with good yields and promising enantioselectivities.

Graphical abstract: Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis

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Article information

DOI
https://doi.org/10.1039/C4OB02056A
Article type
Paper
Submitted
26 Sep 2014
Accepted
29 Sep 2014
First published
30 Sep 2014
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2014,12, 9180-9183

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Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis

A. S. Henderson, J. F. Bower and M. C. Galan, Org. Biomol. Chem., 2014, 12, 9180 DOI: 10.1039/C4OB02056A

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