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Issue 7, 2015
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β-Ketothioamides: efficient reagents in the synthesis of heterocycles

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Abstract

β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds. In the past decade, a number of successful reactions based on KTAs have been developed for the construction of heterocyclic skeletons under mild conditions. This minireview focuses on the annulation reactions of KTAs with dielectrophilic or dinucleophilic reagents. Multicomponent reactions using KTAs to construct various heterocycles are also the major contents in this review.

Graphical abstract: β-Ketothioamides: efficient reagents in the synthesis of heterocycles

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Publication details

The article was received on 23 Sep 2014, accepted on 10 Dec 2014, published on 10 Dec 2014 and first published online on 10 Dec 2014


Article type: Review Article
DOI: 10.1039/C4OB02024C
Citation: Org. Biomol. Chem., 2015,13, 1942-1953
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    β-Ketothioamides: efficient reagents in the synthesis of heterocycles

    W. Guo, L. Wen and M. Li, Org. Biomol. Chem., 2015, 13, 1942
    DOI: 10.1039/C4OB02024C

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