Jump to main content
Jump to site search

Issue 46, 2014
Previous Article Next Article

Remote conformational control of a molecular switch via methylation and deprotonation

Author affiliations

Abstract

Exacting control over conformation in response to an external stimulus is the central focus of molecular switching. Here we describe the synthesis of a series of diphenylacetylene-based molecular switches, and examine their response to covalent modification and deprotonation at remote phenolic positions. A complex interplay between multiple intramolecular hydrogen bond donors and acceptors determines the global conformation.

Graphical abstract: Remote conformational control of a molecular switch via methylation and deprotonation

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Sep 2014, accepted on 08 Oct 2014 and first published on 08 Oct 2014


Article type: Paper
DOI: 10.1039/C4OB01991A
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2014,12, 9384-9388
  •   Request permissions

    Remote conformational control of a molecular switch via methylation and deprotonation

    P. C. Knipe, I. M. Jones, S. Thompson and A. D. Hamilton, Org. Biomol. Chem., 2014, 12, 9384
    DOI: 10.1039/C4OB01991A

Search articles by author

Spotlight

Advertisements