2-Alkanoyl(aroyl)-pyridines have been successfully used for coupling with alkyl vinyl ketones under the influence of TMSOTf providing a facile protocol for the synthesis of substituted indolizines, thus demonstrating the application of ketones as electrophiles in a two component Baylis–Hillman reaction.
D. Basavaiah, G. Veeraraghavaiah and S. S. Badsara, Org. Biomol. Chem., 2014, 12, 1551 DOI: 10.1039/C3OB42064G
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