Jump to main content
Jump to site search

Issue 8, 2014
Previous Article Next Article

A microfluidic photobioreactor array demonstrating high-throughput screening for microalgal oil production

Author affiliations

Abstract

Microalgae are envisioned as a future source of renewable oil. The feasibility of producing high-value biomolecules from microalgae is strongly dependent on developing strains with increased productivity and environmental tolerance, understanding algal gene regulation, and optimizing growth conditions for higher production of target molecules. We present a high-throughput microfluidic microalgal photobioreactor array capable of applying 64 different light conditions to arrays of microscale algal photobioreactors and apply this device to investigate how light conditions influence algal growth and oil production. Using the green colony-forming microalga Botryococcus braunii, the light intensity and light–dark cycle conditions were identified that induced 1.8-fold higher oil accumulation over the typically used culture conditions. Additionally, the studies revealed that the condition under which maximum oil production occurs is significantly different from that of maximum growth. This screening test was accomplished using the developed photobioreactor array at 250 times higher throughput compared to conventional flask-scale photobioreactors.

Graphical abstract: A microfluidic photobioreactor array demonstrating high-throughput screening for microalgal oil production

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 17 Dec 2013, accepted on 23 Jan 2014 and first published on 23 Jan 2014


Article type: Paper
DOI: 10.1039/C3LC51396C
Citation: Lab Chip, 2014,14, 1415-1425
  •   Request permissions

    A microfluidic photobioreactor array demonstrating high-throughput screening for microalgal oil production

    H. S. Kim, T. L. Weiss, H. R. Thapa, T. P. Devarenne and A. Han, Lab Chip, 2014, 14, 1415
    DOI: 10.1039/C3LC51396C

Search articles by author