Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 4, 2014
Previous Article Next Article

Improving the accuracy of single particle ICPMS for measurement of size distributions and number concentrations of nanoparticles by determining analyte partitioning during nebulisation

Author affiliations

Abstract

Application of single particle ICP-MS (spICPMS) for measurement of the size and number concentration, cp, of nanoparticles is currently hampered by insufficient accuracy. The relative contributions of different types of noise to the overall uncertainty during spICPMS measurements of Ag and Au nanoparticle dispersions were quantified showing that the accuracy of spICPMS is mainly limited by the uncertainty in nebulization efficiency (fneb). This uncertainty was improved by correcting fneb for analyte partitioning effects during nebulization, and the calculated Ag and Au nanoparticle sizes were in close agreement with sizes determined by scanning electron microscopy. The duration of the particle events was measured, which allowed correction for incomplete particle events and detector dead time, and determination of the effective dwell time for particle counting. The cp measured with spICPMS agreed with that measured by counting particles deposited on filters, and calculated from the mass concentration of the analyte.

Graphical abstract: Improving the accuracy of single particle ICPMS for measurement of size distributions and number concentrations of nanoparticles by determining analyte partitioning during nebulisation

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 17 Nov 2013, accepted on 20 Jan 2014 and first published on 21 Jan 2014


Article type: Paper
DOI: 10.1039/C3JA50367D
Citation: J. Anal. At. Spectrom., 2014,29, 743-752
  •   Request permissions

    Improving the accuracy of single particle ICPMS for measurement of size distributions and number concentrations of nanoparticles by determining analyte partitioning during nebulisation

    J. Tuoriniemi, G. Cornelis and M. Hassellöv, J. Anal. At. Spectrom., 2014, 29, 743
    DOI: 10.1039/C3JA50367D

Search articles by author