Jump to main content
Jump to site search

Issue 8, 2014
Previous Article Next Article

Visible-light-induced photocatalytic formyloxylation reactions of 3-bromooxindoles with water and DMF: the scope and mechanism

Author affiliations

Abstract

The formyloxylation reaction of 3-bromooxindoles with water and N,N-dimethylformamide (DMF) has been developed in the presence of the photoredox catalyst fac-Ir(ppy)3 under irradiation of visible light at ambient temperature. The reaction provides a straightforward approach to pharmaceutically and synthetically useful 3-formyloxyoxindoles in high yields. The mechanism of this transformation was investigated by fluorescence quenching experiments, “on–off” switching of the light source, labeling experiments, mass spectral analyses and in situ IR experiments.

Graphical abstract: Visible-light-induced photocatalytic formyloxylation reactions of 3-bromooxindoles with water and DMF: the scope and mechanism

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Apr 2014, accepted on 08 May 2014 and first published on 08 May 2014


Article type: Paper
DOI: 10.1039/C4GC00647J
Author version available: Download Author version (PDF)
Citation: Green Chem., 2014,16, 3787-3795
  •   Request permissions

    Visible-light-induced photocatalytic formyloxylation reactions of 3-bromooxindoles with water and DMF: the scope and mechanism

    Y. Zou, W. Guo, F. Liu, L. Lu, J. Chen and W. Xiao, Green Chem., 2014, 16, 3787
    DOI: 10.1039/C4GC00647J

Search articles by author

Spotlight

Advertisements