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Issue 6, 2016
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A novel biocompatible europium ligand for sensitive time-gated immunodetection

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Abstract

We describe the synthesis of a novel hydrophilic derivative of a tetradentate β-diketone europium ligand that was used to prepare an immunoconjugate probe against Giardia lamblia cysts. We used a Gated Autosynchronous Luminescence Detector (GALD) to obtain high quality delayed luminescence images of cells 30-fold faster than ever previously reported.

Graphical abstract: A novel biocompatible europium ligand for sensitive time-gated immunodetection

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Publication details

The article was received on 13 Aug 2015, accepted on 20 Nov 2015 and first published on 20 Nov 2015


Article type: Communication
DOI: 10.1039/C5CC06811H
Citation: Chem. Commun., 2016,52, 1154-1157
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    A novel biocompatible europium ligand for sensitive time-gated immunodetection

    N. Sayyadi, R. E. Connally and A. Try, Chem. Commun., 2016, 52, 1154
    DOI: 10.1039/C5CC06811H

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