Issue 25, 2015
From the journal:

Chemical Communications

Tuning the selectivity of triplex DNA receptors†

Haidong Huang*a  and  Peter C. Tlatelpaa  

* Corresponding authors

a Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ, USA
E-mail: haidong.huang@njit.edu
Fax: +1-973-596-3586
Tel: +1-973-596-3576

Abstract

Effects of hydrogen bonding clamps on the selectivity of triplex DNA receptors were studied. Incorporation of a 5-methyl-2-thiocytosine base to the parallel homopyrimidine region of a triplex receptor enabled selective molecular recognition of an inosine ligand.

Graphical abstract: Tuning the selectivity of triplex DNA receptors

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Article information

DOI
https://doi.org/10.1039/C4CC07805E
Article type
Communication
Submitted
02 Oct 2014
Accepted
23 Oct 2014
First published
23 Oct 2014

Chem. Commun., 2015,51, 5337-5339

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Tuning the selectivity of triplex DNA receptors

H. Huang and P. C. Tlatelpa, Chem. Commun., 2015, 51, 5337 DOI: 10.1039/C4CC07805E

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