Jump to main content
Jump to site search

Issue 97, 2014
Previous Article Next Article

Stereoselective synthesis of ε-lactones or spiro-heterocycles through NHC-catalyzed annulation: divergent reactivity by catalyst control

Author affiliations

Abstract

NHC-catalyzed divergent annulation of enals with heterocyclic enones was developed to produce benzofuran/indole-containing ε-lactones or spiro-heterocycles in a highly diastereo- and enantioselective fashion. The chemo-selectivity controlled by the chiral catalyst backbone is particularly noteworthy.

Graphical abstract: Stereoselective synthesis of ε-lactones or spiro-heterocycles through NHC-catalyzed annulation: divergent reactivity by catalyst control

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Oct 2014, accepted on 16 Oct 2014 and first published on 16 Oct 2014


Article type: Communication
DOI: 10.1039/C4CC07788A
Citation: Chem. Commun., 2014,50, 15309-15312
  •   Request permissions

    Stereoselective synthesis of ε-lactones or spiro-heterocycles through NHC-catalyzed annulation: divergent reactivity by catalyst control

    M. Wang, Z. Rong and Y. Zhao, Chem. Commun., 2014, 50, 15309
    DOI: 10.1039/C4CC07788A

Search articles by author

Spotlight

Advertisements