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Issue 2, 2015
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Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

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Abstract

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to hitherto reported compounds.

Graphical abstract: Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

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Publication details

The article was received on 01 Sep 2014, accepted on 11 Nov 2014 and first published on 11 Nov 2014


Article type: Communication
DOI: 10.1039/C4CC06886F
Citation: Chem. Commun., 2015,51, 391-394
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    Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

    R. Nishihara, H. Suzuki, E. Hoshino, S. Suganuma, M. Sato, T. Saitoh, S. Nishiyama, N. Iwasawa, D. Citterio and K. Suzuki, Chem. Commun., 2015, 51, 391
    DOI: 10.1039/C4CC06886F

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