Silver-catalyzed decarboxylative acylfluorination of styrenes in aqueous media†
Abstract
A mild catalytic decarboxylative acylfluorination of styrenes with α-oxocarboxylic acids and Selectfluor is reported. This operationally simple and efficient method provides a fundamentally novel approach toward the synthesis of β-fluorinated 3-aryl ketones with a wide range of substrate scope.