Issue 55, 2014

Silver-catalyzed decarboxylative acylfluorination of styrenes in aqueous media

Abstract

A mild catalytic decarboxylative acylfluorination of styrenes with α-oxocarboxylic acids and Selectfluor is reported. This operationally simple and efficient method provides a fundamentally novel approach toward the synthesis of β-fluorinated 3-aryl ketones with a wide range of substrate scope.

Graphical abstract: Silver-catalyzed decarboxylative acylfluorination of styrenes in aqueous media

Supplementary files

Article information

Article type
Communication
Submitted
16 Apr 2014
Accepted
19 May 2014
First published
19 May 2014

Chem. Commun., 2014,50, 7382-7384

Silver-catalyzed decarboxylative acylfluorination of styrenes in aqueous media

H. Wang, L. Guo and X. Duan, Chem. Commun., 2014, 50, 7382 DOI: 10.1039/C4CC02800G

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