Issue 51, 2014
From the journal:

Chemical Communications

A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles†

Siva Senthil Kumar Boominathan,a   Wan-Ping Hu,b   Gopal Chandru Senadi,a   Jaya Kishore Vandavasia  and  Jeh-Jeng Wang*a  

* Corresponding authors

a Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan
E-mail: jjwang@kmu.edu.tw

b Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan

Abstract

A practical one-pot hypoiodite catalysed oxidative cyclization approach to synthesize α-ketobenzoxazole derivatives was successfully developed. This operationally simple protocol utilizes easily-accessible starting materials and has a broad substrate scope with excellent yields.

Graphical abstract: A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles

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Article information

DOI
https://doi.org/10.1039/C4CC02425G
Article type
Communication
Submitted
02 Apr 2014
Accepted
02 May 2014
First published
02 May 2014

Chem. Commun., 2014,50, 6726-6728

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A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles

S. S. K. Boominathan, W. Hu, G. C. Senadi, J. K. Vandavasi and J. Wang, Chem. Commun., 2014, 50, 6726 DOI: 10.1039/C4CC02425G

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