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Issue 57, 2014
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Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

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Abstract

Based on the protective properties of carbon nanoparticles for aptamers against the digestion of nuclease, we have developed a nuclease-assisted target recycling signal amplification method for highly sensitive detection of biomolecules, such as ATP and kanamycin. The high binding specificity between aptamers and targets leads to excellent selectivity of the assay.

Graphical abstract: Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

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Publication details

The article was received on 25 Mar 2014, accepted on 22 May 2014 and first published on 22 May 2014


Article type: Communication
DOI: 10.1039/C4CC02184C
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2014,50, 7646-7648
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    Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

    X. Lin, L. Cui, Y. Huang, Y. Lin, Y. Xie, Z. Zhu, B. Yin, X. Chen and C. J. Yang, Chem. Commun., 2014, 50, 7646
    DOI: 10.1039/C4CC02184C

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