Issue 42, 2014

Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

Abstract

A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time. This transformation offers an alternative method for the synthesis of polysubstituted quinoline.

Graphical abstract: Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

Supplementary files

Article information

Article type
Communication
Submitted
05 Feb 2014
Accepted
25 Mar 2014
First published
25 Mar 2014

Chem. Commun., 2014,50, 5583-5585

Author version available

Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

W. Zhou and J. Lei, Chem. Commun., 2014, 50, 5583 DOI: 10.1039/C4CC00939H

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