Issue 24, 2014
From the journal:

Chemical Communications

Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene†

Dong-Dong Zheng,a   Ding-Yi Fu,a   Yuqing Wu,*a   Yu-Long Sun,a   Li-Li Tan,a   Ting Zhou,a   Shi-Qi Ma,b   Xiao Zhab  and  Ying-Wei Yang*a  

* Corresponding authors

a State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, China
E-mail: yqwu@jlu.edu.cn, ywyang@jlu.edu.cn

b Sichuan Tumor Hospital & Institute, Chengdu, China

Abstract

Pillarenes and calixarenes showed obvious inhibition of HPV16 L1 pentamer formation via their selective binding to Arg and Lys residues at the monomer interface, which was reversible after the release of cyclic arenes. Pillarenes are more effective than calixarenes in terms of the inhibition efficiency, attributing to the different kinetics and binding affinity.

Graphical abstract: Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC49789E
Article type
Communication
Submitted
26 Dec 2013
Accepted
29 Jan 2014
First published
29 Jan 2014

Chem. Commun., 2014,50, 3201-3203

Permissions

Request permissions

Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene

D. Zheng, D. Fu, Y. Wu, Y. Sun, L. Tan, T. Zhou, S. Ma, X. Zha and Y. Yang, Chem. Commun., 2014, 50, 3201 DOI: 10.1039/C3CC49789E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements