Issue 18, 2014

nBu4NI-Catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones

Abstract

nBu4NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.

Graphical abstract: nBu4NI-Catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones

Supplementary files

Article information

Article type
Communication
Submitted
21 Nov 2013
Accepted
08 Jan 2014
First published
09 Jan 2014

Chem. Commun., 2014,50, 2367-2369

nBu4NI-Catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones

Y. Lv, Y. Li, T. Xiong, Y. Lu, Q. Liu and Q. Zhang, Chem. Commun., 2014, 50, 2367 DOI: 10.1039/C3CC48887J

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