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Issue 11, 2014
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Touch spray mass spectrometry for in situ analysis of complex samples

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Abstract

Touch spray, a spray-based ambient in situ ionization method, uses a small probe, e.g. a teasing needle to pick up sample and the application of voltage and solvent to cause field-induced droplet emission. Compounds extracted from the microsample are incorporated into the sprayed micro droplets. Performance tests include disease state of tissue, microorganism identification, and therapeutic drug quantitation. Chemical derivatization is performed simultaneously with ionization.

Graphical abstract: Touch spray mass spectrometry for in situ analysis of complex samples

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Supplementary files

Publication details

The article was received on 25 Mar 2014, accepted on 09 Apr 2014 and first published on 23 Apr 2014


Article type: Paper
DOI: 10.1039/C4AN00548A
Author version available: Download Author version (PDF)
Citation: Analyst, 2014,139, 2714-2720
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    Touch spray mass spectrometry for in situ analysis of complex samples

    K. S. Kerian, A. K. Jarmusch and R. G. Cooks, Analyst, 2014, 139, 2714
    DOI: 10.1039/C4AN00548A

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