Issue 12, 2014

Target-initiated impedimetric proximity ligation assay with DNAzyme design for in situ amplified biocatalytic precipitation

Abstract

A target-initiated proximity ligation assay (PLA) protocol accompanying DNAzyme formation was for the first time designed for ultrasensitive impedimetric monitoring of heavy metal ions (silver ions were used in this case) by coupling with enzymatic biocatalytic precipitation.

Graphical abstract: Target-initiated impedimetric proximity ligation assay with DNAzyme design for in situ amplified biocatalytic precipitation

Supplementary files

Article information

Article type
Communication
Submitted
21 Mar 2014
Accepted
13 Apr 2014
First published
14 Apr 2014

Analyst, 2014,139, 2998-3001

Author version available

Target-initiated impedimetric proximity ligation assay with DNAzyme design for in situ amplified biocatalytic precipitation

J. Tang, M. Lu and D. Tang, Analyst, 2014, 139, 2998 DOI: 10.1039/C4AN00523F

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