Jump to main content
Jump to site search

Issue 36, 2017
Previous Article Next Article

Intramolecular hydrogen bonding in conformationally semi-rigid α-acylmethane derivatives: a theoretical NMR study

Author affiliations

Abstract

Conformational mobility is a core property of organic compounds, and conformational analysis has become a pervasive tool for synthetic design. In this work, we present experimental and computational (employing Density Functional Theory) evidence for unusual intramolecular hydrogen bonding interactions in a series of α-acylmethane derivatives, as well as a discussion of the consequences thereof for their NMR spectroscopic properties.

Graphical abstract: Intramolecular hydrogen bonding in conformationally semi-rigid α-acylmethane derivatives: a theoretical NMR study

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Jul 2017, accepted on 18 Aug 2017 and first published on 18 Aug 2017


Article type: Paper
DOI: 10.1039/C7OB01834G
Citation: Org. Biomol. Chem., 2017,15, 7572-7579
  • Open access: Creative Commons BY license
  •   Request permissions

    Intramolecular hydrogen bonding in conformationally semi-rigid α-acylmethane derivatives: a theoretical NMR study

    A. J. Mota, J. Neuhold, M. Drescher, S. Lemouzy, L. González and N. Maulide, Org. Biomol. Chem., 2017, 15, 7572
    DOI: 10.1039/C7OB01834G

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements