Issue 22, 2014

Fluorous enzymatic synthesis of phosphatidylinositides

Abstract

A fluorous tagging strategy coupled with enzymatic synthesis is introduced to efficiently synthesize multiple phosphatidylinositides, which are then directly immobilized on a fluorous polytetrafluoroethylene (PTFE) membrane to probe protein–lipid interactions.

Graphical abstract: Fluorous enzymatic synthesis of phosphatidylinositides

Supplementary files

Article information

Article type
Communication
Submitted
02 Jan 2014
Accepted
28 Jan 2014
First published
29 Jan 2014

Chem. Commun., 2014,50, 2928-2931

Author version available

Fluorous enzymatic synthesis of phosphatidylinositides

W. Huang, A. Proctor, C. E. Sims, N. L. Allbritton and Q. Zhang, Chem. Commun., 2014, 50, 2928 DOI: 10.1039/C4CC00022F

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