Issue 65, 2017
From the journal:

Chemical Communications

A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers†

Jiuxing Li,a   Zhuangqiang Gao,ab   Haihang Ye,a   Shulin Wan,a   Meghan Pierce,c   Dianping Tang ORCID logo b  and  Xiaohu Xia ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Michigan Technological University, Houghton, Michigan 49931, USA
E-mail: xiaxh@mtu.edu

b Key Laboratory of Analysis and Detection for Food Safety (Fujian Province & Ministry of Education), Collaborative Innovation Center of Detection Technology for Haixi Food Safety and Products (Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China

c Department of Chemical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA

Abstract

A non-enzyme cascade amplification strategy, based on the dissolution of Ag nanoparticles and a Pt nanocube-catalyzed reaction, for colorimetric assay of disease biomarkers was developed. This strategy overcomes the intrinsic limitations of enzymes involved in conventional enzymatic amplification techniques, thanks to the utilization of noble-metal nanostructures with superior properties.

Graphical abstract: A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers

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Article information

DOI
https://doi.org/10.1039/C7CC04521B
Article type
Communication
Submitted
11 Jun 2017
Accepted
06 Jul 2017
First published
06 Jul 2017

Chem. Commun., 2017,53, 9055-9058

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A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers

J. Li, Z. Gao, H. Ye, S. Wan, M. Pierce, D. Tang and X. Xia, Chem. Commun., 2017, 53, 9055 DOI: 10.1039/C7CC04521B

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