Jump to main content
Jump to site search

Issue 24, 2013
Previous Article Next Article

Nanoscale organization of proteins via block copolymer lithography and non-covalent bioconjugation

Author affiliations

Abstract

Thin films of cylinder-forming biotinylated poly(ethylene glycol)-polystyrene (PEG-b-PS) block copolymers were studied as a means to produce protein patterns. The orientation of the PEG cylinders depended on the end group functionality as well as on the preparation conditions. In the case of perpendicular cylinders, immobilization of single streptavidin molecules could be achieved. This immobilization was controlled by varying the amount of biotin in the films by mixing with non-functional PEG-b-PS.

Graphical abstract: Nanoscale organization of proteins via block copolymer lithography and non-covalent bioconjugation

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Mar 2013, accepted on 01 May 2013 and first published on 01 May 2013


Article type: Communication
DOI: 10.1039/C3TB20411A
Citation: J. Mater. Chem. B, 2013,1, 3026-3030
  •   Request permissions

    Nanoscale organization of proteins via block copolymer lithography and non-covalent bioconjugation

    I. C. Reynhout, G. Delaittre, H. Kim, R. J. M. Nolte and J. J. L. M. Cornelissen, J. Mater. Chem. B, 2013, 1, 3026
    DOI: 10.1039/C3TB20411A

Search articles by author

Spotlight

Advertisements