Jump to main content
Jump to site search

Issue 3, 2014
Previous Article Next Article

Spontaneous unilamellar polymer vesicles in aqueous solution

Author affiliations

Abstract

A unilamellar polymeric vesicle is a self-assembled structure of a block copolymer that forms a spherical single bilayer structure with a hydrophobic interlayer and a hydrophilic surface. Due to their enhanced colloidal stability and mechanical property, controllable surface functionality, or tunable membrane thickness, polymeric vesicles are useful in nano and bio-science, providing potential applications as nanosized carriers for catalysts, drugs, and enzymes. For fabrication of a unilamellar vesicle, however, preparative procedures with a few steps are inherently required. Herein, without complicated preparative procedures, we report spontaneous unilamellar polymeric vesicles with nanometer sizes (<100 nm), which are prepared by simply mixing a triblock copolymer, Pluronic P85 (PEO26PPO40PEO26), and an organic derivative, 5-methyl salicylic acid (5mS), in aqueous solution. Depending on the 5mS concentration and the temperature, the P85–5mS mixtures presented various self-assembled nanostructures such as spherical and cylindrical micelles or vesicles, which were characterized by small angle neutron scattering and cryo-TEM, resulting in a phase diagram drawn as a function of temperature and the 5mS concentration. Interestingly the critical temperature for the micelle-to-vesicle phase transition was easily controlled by varying the 5mS concentration, i.e. it was decreased with increasing the 5mS concentration.

Graphical abstract: Spontaneous unilamellar polymer vesicles in aqueous solution

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Sep 2013, accepted on 08 Nov 2013 and first published on 08 Nov 2013


Article type: Paper
DOI: 10.1039/C3SM52519H
Citation: Soft Matter, 2014,10, 484-490
  •   Request permissions

    Spontaneous unilamellar polymer vesicles in aqueous solution

    T. Kim, C. Song, Y. Han, J. Jang and M. C. Choi, Soft Matter, 2014, 10, 484
    DOI: 10.1039/C3SM52519H

Search articles by author

Spotlight

Advertisements