Issue 26, 2013
From the journal:

RSC Advances

Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics†

Yuqiong Li,a   Ryan T. K. Kwok,b   Ben Zhong Tang*abc  and  Bin Liu*ad  

* Corresponding authors

a Institute of Materials Research Engineering, 3 Research Link, Singapore
Fax: 65 6872 0785
Tel: 65 6874 8111

b Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China
E-mail: tangbenz@ust.hk
Fax: 852 2358 1594
Tel: 852 2358 7375

c SCUT-HKUST Joint Research Laboratory, Guangdong Innovative Research Team, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China

d Department of Chemical and Biomolecular Engineering, 4 Engineering Drive 4, National University of Singapore, Singapore
E-mail: cheliub@nus.edu.sg
Fax: 65 6779 1936
Tel: 65 6516 3044

Abstract

We report a new fluorescent light-up probe design strategy by conjugating fluorogens with aggregation-induced emission (AIE) characteristics, e.g. tetraphenylethene with a single-stranded oligonucleotide for homogeneous specific complementary DNA detection in solution.

Graphical abstract: Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics

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Article information

DOI
https://doi.org/10.1039/C3RA41983E
Article type
Communication
Submitted
16 Feb 2013
Accepted
02 May 2013
First published
02 May 2013

RSC Adv., 2013,3, 10135-10138

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Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics

Y. Li, R. T. K. Kwok, B. Z. Tang and B. Liu, RSC Adv., 2013, 3, 10135 DOI: 10.1039/C3RA41983E

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