Issue 25, 2013
From the journal:

RSC Advances

Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid†

Maria Cherepanova,a   Loránd Kiss,a   Reijo Sillanpääc  and  Ferenc Fülöp*ab  

* Corresponding authors

a Institute of Pharmaceutical Chemistry, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary

b Stereochemistry Research Group of the Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary

c Department of Chemistry, University of Jyväskylä, FIN-40014, Jyväskylä, Finland
E-mail: fulop@pharm.u-szeged.hu

Abstract

Difunctionalized cispentacin derivatives with two new stereogenic centres have been synthesized from a diendo-norbornene β-amino acid in a stereocontrolled route, involving C–C double bond functionalization by dihydroxylation, followed by oxidative ring cleavage and transformation of the dialdehyde intermediates through a Wittig reaction.

Graphical abstract: Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3RA41963K
Article type
Paper
Submitted
30 Jan 2013
Accepted
23 Apr 2013
First published
16 May 2013

RSC Adv., 2013,3, 9757-9763

Permissions

Request permissions

Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid

M. Cherepanova, L. Kiss, R. Sillanpää and F. Fülöp, RSC Adv., 2013, 3, 9757 DOI: 10.1039/C3RA41963K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements