Jump to main content
Jump to site search

Issue 26, 2013
Previous Article Next Article

Electric actuating valves incorporated into an all glass-based microchip exploiting the flexibility of ultra thin glass

Author affiliations

Abstract

In the field of “lab-on-a-chip”, sophisticated valves are extremely important to manipulate small-volume samples in a microchip. Currently, the most commonly used valves utilize polydimethylsiloxane (PDMS), exploiting its elastomeric property. Although polymer-based valves are very sophisticated and convenient, they also have several disadvantages such as chemical and physical instability and an inherent optical detection limit. With respect to these issues, glass is the most common material utilized to create multi-purpose integrated chemical systems. However, glass is very hard and difficult to incorporate valves into a glass microchip. To overcome this problem, I propose to use a very flexible, ultra thin glass sheet fabricated using an overflow fusion downdraw process to realize a minimum thickness of a few micrometers. In this report, I describe an ultra thin glass-based valve installed in an entirely glass-based microchip. Since ultra thin glass is very fragile, manipulation is difficult especially in liquid. Therefore, methods for ultra thin glass manipulation and fabrication using thermal fusion bonding were established. The valve function was demonstrated using bimorph-type piezo actuators. Valve function in a linear channel and switching valve function were demonstrated. The durable pressure was 3.0 kPa and the response time was about 0.12 s, which was shorter than that reported for similar previous PDMS-based valves. I expect that this device could be utilized for a wide range of applications that require a glass microchip.

Graphical abstract: Electric actuating valves incorporated into an all glass-based microchip exploiting the flexibility of ultra thin glass

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Mar 2013, accepted on 10 Apr 2013 and first published on 10 Apr 2013


Article type: Paper
DOI: 10.1039/C3RA41218K
Citation: RSC Adv., 2013,3, 10213-10220
  •   Request permissions

    Electric actuating valves incorporated into an all glass-based microchip exploiting the flexibility of ultra thin glass

    Y. Tanaka, RSC Adv., 2013, 3, 10213
    DOI: 10.1039/C3RA41218K

Search articles by author

Spotlight

Advertisements